Job Description

Job Title: Vice President, Translational Science - Immunology
Location: San Diego, CA

Company Overview:
A next-generation biotechnology company based in San Diego is leveraging a proprietary platform to discover and develop small molecule therapeutics targeting traditionally undruggable proteins. This innovative platform enables precision targeting of disease-relevant proteins with first-in-class mechanisms of action.

With a rapidly advancing pipeline in immunology, the organization is positioned to translate groundbreaking science into transformative clinical outcomes. The company culture values scientific rigor, creative problem-solving, and a highly collaborative environment.

Position Summary:
The organization is seeking an experienced and visionary Vice President, Translational Science - Immunology to lead the strategic and operational advancement of immunology programs from late discovery through IND-enabling studies and into early clinical development. This individual will act as a critical bridge between discovery and development teams, crafting data-driven translational strategies that support clinical entry and early proof of concept.

The ideal candidate will bring deep immunology expertise, a successful track record in translational science, and direct experience in moving therapeutics from preclinical stages into clinical trials in autoimmune or related diseases.

Key Responsibilities:

Drive the translational strategy for immunology programs through IND and early clinical development.

Lead design and execution of preclinical translational studies, including biomarker development and patient stratification approaches.

Partner cross-functionally with Discovery, Preclinical Development, Clinical Development, Regulatory, and Program Management to align program goals and ensure seamless execution.

Translate mechanistic insights into clinically actionable endpoints to support development decisions and regulatory interactions.

Interpret complex data sets from various platforms (flow cytometry, transcriptomics, immunoassays, etc.) to guide program advancement.

Represent Translational Science on cross-functional teams and senior leadership discussions.

Build and mentor a high-performing translational research team.

Engage with external collaborators, CROs, and advisors to extend translational capabilities.

Required Qualifications:

Ph.D., M.D./Ph.D., or equivalent in Immunology, Cell Biology, or a related field.

15+ years of biotech or pharma experience, with a strong background in immunology and at least 8 years in a leadership

Previous experience succesfully taking pre clinical products to clinical trial

#LI#OG1

Job Tags

Permanent employment,

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